Men across the globe have for centuries defined their happiness in relation to sex. What is a man if he cannot grunt and imitate a baboon in ritual mating? Imagine if a male suffered from the inability to do the activity which brought them such happiness? Erectile dysfunction, commonly known as impotence, is a condition which affects more males than you think. There is something to help. Tadalafil is the 3rd most effective treatment for penile dysfunction after other well-known brands as Viagra and Levitra. Tadalafil has a 36 hour effect, and thus has been branded “the weekend pill” similar to the popular female birth control pill. Except that instead of harboring sexual urges, Tadalafil Helps males to perform and satisfy themselves and their respective partners. Tadalafil, like Viagra and Levitra, works by use of IC351, a PDE5 enzyme inhibitor (means that it prohibits the enzyme which triggers penile arousal from being released).
Most erectile dysfunction drugs use IC351 as their basic process. Discovered in 1994 by scientists, sildenafil citrate, a white crystalline powder (probably if found in raw form on a table would be mistaken as Crack Cocaine by suspicious parents, or suspicious partners…ha-ha) which is the root of how most penile dysfunction drugs work. One significant advantage Tadalafil, or Cialis as known in the pharmaceutical industry, is that Tadalafil works up to 36 hours. Compare that to Viagra (8 hours). How any of these penile enhancement drugs work is comparable to what a cup of tea with milk does for you before bed. There’s a lot of fancy shmancy scientific wording you can research to know the physiological mechanics, but I’ll break it down for ya as I’m sure you don’t have the time or will to do that (unless you’re an actual scientist in which case Please Speak in Common English the next time you talk to people! Just because some of us can understand you doesn’t mean any of us Want To! I am educated in the world of science, but I don’t have a stick up my ass which forces me to say things like guanylate cyclase in daily conversation. Mmmmk? By the way: Great Work! Keep it up.) Ok so back to how it all works. Tadalafil stops the release of PDE5, which is mainly found in the artery lining of the smooth muscle tissue (muscle wall) of the penis and the lungs. This enzyme causes tension in these two areas of the body, and if an individual has too high of an amount of PDE5 it can cause a stress of the tissues in this case the penis which make it impossible for an erection to occur. Tadalafil inserts sildenatil which relaxes the blood vessels in the penile wall and allows for an erection. Ok, so how does an original erection occur? Well pornography and thongs aside, medically an erection in a male occurs when the parasympathetic nervous system is aroused by tiny chemical impulses (usually in response to a thong on flesh or a pretty lady =0) , these impulses excite the body into literally having all the blood rush into the arterial wall of the penis, enlarging it and cause it to grow in size and vertical velocity. The Erection, otherwise known as a “hard-on”. Why is it hard? Well the name comes from the blood vessels which surround the interior of the penis, when those vessels are full of blood, the entire penis becomes rigid. Like how if you fill a balloon with air you’ll notice the balloon’s surface becomes tighter and firmer, and bigger. This isn’t magic people, its basic physiology. Your body is a Beautiful Machine. Once the PNS is activated, nitric oxide is released which then binds to receptors (compare to a tv antenna) of the enzyme guanylate cyclase. The cyclase then leads to increased levels of cyclic guanosine monophosphate (cGMP)-sounds cool huh like a bomb-which essentially relaxes the smooth muscle (called vasodilatation) lining found in the penile wall (called the corpus cavernosum), leading to a huge inflow of blood, and finally an Erection. Systematic like a clock. Pretty Beautiful.
There is an enzympe-phosphodiesterase type 5 (PDE5 as previously mentioned) which if overly high in amount within the male penis-degrades cGMP production and makes it impossible for the penis to relax to allow for an influx of blood flow. Tadalafil inhibits (blocks) this enzyme from being released, allowing nature’s natural process of penile erection to proceed as the prophecy foresees. Tadalafil’s chemical structure is very similar to that of cGMP, and it acts as a binding agent (think of a cop vs. a criminal) to provide competition to PDE5, (imagine the cop beating the criminal and arresting him/her). This fierce battle allows for further production of cGMP, making arousal although an assisted process, still natural. Tadalafil’s process also helps to produce better erections overall in comparison to a normal male. (Just think, Tadalafil provides a double dose of extra strength to the penis). Tadalafil isn’t some scary medicine that acts when unprovoked. It Will Not Work unless the male bearing the discussed penis is first sexually stimulated in some way. Without sexual stimulation, the PNS cannot be activated, and the nitric oxide, and consequently cGMP cannot be released. Tadalafil will not cause an erection unless provoked. Like a cop fighting crime. Do no bad and you’ll face no grief.
Tadalafil also has some other theoretical uses. It is currently undergoing clinical testing for being a cure for pulmonary hypertension. Pulmonary hypertension is an increase in blood pressure, which leads to shortness of breath, exhaustion, dizziness, and possibly heart failure. Tadalafil can do to the lungs what it does to the penis, relax blood vessels to allow for air and eliminate the risks of heart or lung failure within pulmonary hypertension.
Tadalafil’s side effects, according to research done by the Food and Drug Administration have been found to be: headache, indigestion, back pain, muscle aches, flushing, and stuffy or runny nose. So think thrice, as always, before taking any drug. Tadalafil also in some clinical studies can lead to vision impairment in selected individuals.
In the case that you find yourself surrounded by ecstasy pills at a crazy frat party, make sure you don’t confuse LSD or E for Tadalafil. Tadalafil is a yellow tablet, with a thin coating, shaped like an almond, and always either in 5, 10, or 20 milligram doses (the dose is always visible in small print on the tablet, usually in dark-brown letters). 20 milligrams may not seem like much, a typical Viagra pill is 100 mg. But chemistry is a fascinating thing. You do it the right way, and size/quantity does not measure effectiveness. So Don’t Take More Than The Recommended Dosage! You might get a hard on for a week! As appealing as that may sound to some of you, medically, you could wind up seriously injured in a hospital oozing with questionable odours and devoid of cute nurses.
Another Disclaimer: Do Not take organic nitrates (such as goat weed, spanish fly, or other sexual lubricants) within 48 hours of taking Tadalafil. Because of the low blood pressure caused by Tadalafil, these sexual substrates may cause life-threatening hypotension. If you have stupidly or by mistake done this, get medical attention Immediately. Call your emergency service operator Immediately if you experience heart pulls/attacks.
However, it is strongly advised by this writer that males suffering from this condition should first look to their inner problems and decipher whether there is a bigger cause of their dysfunction. Clinical studies have shown that Erectile dysfunction can be caused by psychological as well as physiological damage. Have you suffered a negligent childhood? Have your previous girlfriends not appreciated you in full for all that you are? Lack of love can lead to deep psychological trauma, including but not limited to, Yes, Impotence. You are not defined by your success, sexual record tally, masculinity or other stereotypical labels assigned to the modern male. You are so much more than that! Tadalafil is an effective drug. But you are the ultimate ruler of your body. Make sure you examine yourself from within, before you go seeking help externally. Keep in mind that Eli Lilly the big controversial drug company has made over 1.2 billion over this original discovery of sildenafil citrate. Something which makes One industry so much money, you should always be in slight suspicion of. Remember that before you go to a drug, see if there is any alternative medicine, or herbal cure which can remedy your condition. Every pill you buy contributes to the mass drug companies at large, and their ultimate motive regardless of how many illusive pretty speeches they give, is Profit. Profit, does not always equate Health of their Consumers. Just remember that. With drug companies, and all mass companies who claim to do things to “help people”. Always do your Own research and Think Thrice. If you do decide to go the penile dysfunction drug help way, I recommend Tadalafil as it is the most effective product out there.